DOKK / manpages / debian 12 / seqan-apps / pair_align.1.en
PAIR_ALIGN(1) PAIR_ALIGN(1)

pair_align - Pairwise alignment

pair_align [OPTIONS] -s IN

The program allows one to align two sequences using dyamic programming alignment algorithms while tweaking various parameters.

Display the help message.
Display version information.

FASTA file with two sequences. Valid filetypes are: .frn, .fna, .ffn, .fasta, .faa, and .fa.
Sequence alphabet. One of protein, dna, rna, and text. Default: protein.
DP alignment method: Needleman-Wunsch, Gotoh, Smith-Waterman, Longest Common Subsequence One of nw, gotoh, sw, and lcs. Default: gotoh.
Output filename. Valid filetypes are: .msf, .frn, .fna, .ffn, .fasta, .faa, and .fa. Default: out.fasta.

Gap open penalty. Default: -11.
Gap extension penalty. Default: -1.
Score matrix.
Match score. Default: 5.
Mismatch penalty. Default: -4.

Lower diagonal.
Upper diagonal.

Alignment configuration. One of ffff, ffft, fftf, fftt, ftff, ftft, fttf, fttt, tfff, tfft, tftf, tftt, ttff, ttft, tttf, and tttt.

The alignment configuration is a string of four characters, each being either t or f. All combinations are allowed. The meaning is as follows.

First row initialized with 0s.
First column initialized with 0s.
Search last column for maximum.
Search last row for maximum.
pair_align 1.3.8 [tarball]